Title of article :
A facile Lewis acid-promoted allylation of azetidin-2-ones
Author/Authors :
Bari، نويسنده , , S.S. and Venugopalan، نويسنده , , Surinder P. and Arora، نويسنده , , Renu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
Exposure of 3α-chloro-3-phenylthioazetidin-2-ones and allyltrimethylsilane to a Lewis acid promotes a remarkably facile and stereoselective C-3 allylation to give 3α-allyl-3-phenylthioazetidin-2-ones 4 in excellent yield. These allylated azetidin-2-ones undergo smooth desulphurization with tri-n-butyltin hydride or Raney-nickel producing cis-3-allyl- and cis-3-propylazetidin-2-ones.
Keywords :
Lewis acid , allylation , Allylsilane , Desulphurisation , azetidinones , allylstannane
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
