Title of article
A facile Lewis acid-promoted allylation of azetidin-2-ones
Author/Authors
Bari، نويسنده , , S.S. and Venugopalan، نويسنده , , Surinder P. and Arora، نويسنده , , Renu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
895
To page
897
Abstract
Exposure of 3α-chloro-3-phenylthioazetidin-2-ones and allyltrimethylsilane to a Lewis acid promotes a remarkably facile and stereoselective C-3 allylation to give 3α-allyl-3-phenylthioazetidin-2-ones 4 in excellent yield. These allylated azetidin-2-ones undergo smooth desulphurization with tri-n-butyltin hydride or Raney-nickel producing cis-3-allyl- and cis-3-propylazetidin-2-ones.
Keywords
Lewis acid , allylation , Allylsilane , Desulphurisation , azetidinones , allylstannane
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1660347
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