Author/Authors :
Gibson، نويسنده , , Colin L. and La Rosa، نويسنده , , Salvatore and Suckling، نويسنده , , Colin J.، نويسنده ,
Abstract :
The linking of pyrimidines to polystyrene supports via either a 2- or 4-thioether provides access to pteridines through solid-phase synthesis. Oxidative cleavage (dimethyldioxirane) followed by nucleophilic substitution by amines, azide, or water completes a traceless synthesis of pteridines.
