Title of article
Stereochemistry of iejimalide B
Author/Authors
Tsuda، نويسنده , , Masashi and Nozawa، نويسنده , , Kohei and Shimbo، نويسنده , , Kazutaka and Ishiyama، نويسنده , , Haruaki and Fukushi، نويسنده , , Eri and Kawabata، نويسنده , , Jun-ka Kobayashi، نويسنده , , Junʹichi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
1395
To page
1399
Abstract
The absolute configurations at five chiral centers, except for C-32(S) reported previously, in iejimalide B (1), a potent cytotoxic 24-membered macrolide isolated from a tunicate Eudistoma cf. rigida, were assigned as 4R, 9S, 17S, 22S, and 23S on the basis of detailed analysis of NMR data and chemical means. Furthermore, the structure of iejimalide B was revised from 2 (original: 13E) to its 13Z-isomer (1).
Keywords
macrolide , absolute configuration , tunicate
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1660616
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