Regioselective electrophilic trifluoromethylation of substituted anilines and derivatives in superacid
Author/Authors :
Debarge، نويسنده , , Sébastien and Violeau، نويسنده , , Bruno and Bendaoud، نويسنده , , Nohair and Jouannetaud، نويسنده , , Marie-Paule and Jacquesy، نويسنده , , Jean-Claude، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Pages :
4
From page :
1747
To page :
1750
Abstract :
In a one pot procedure, treatment of chloro or methyl substituted acetanilides in HF/SbF5/CCl4 followed by addition of HF/pyridine yields trifluoromethyl derivatives with high regioselectivity.
