Author/Authors :
Hallur Gurulingappa، نويسنده , , Hallur and Buckhaults، نويسنده , , Phillip and Kumar، نويسنده , , Srinivas K. and Kinzler، نويسنده , , Kenneth W. and Vogelstein، نويسنده , , Bert and Khan، نويسنده , , Saeed R.، نويسنده ,
Abstract :
Aminophosphinic acid derivatives were synthesized as potential inhibitors of renal dipeptidase, an enzyme overexpressed in benign and malignant colon tumors. Several compounds showed potent enzyme-inhibitory activity.