Title of article :
Total syntheses of hyacinthacine A2 and 7-deoxycasuarine by cycloaddition to a carbohydrate derived nitrone
Author/Authors :
Cardona، نويسنده , , Francesca and Faggi، نويسنده , , Enrico and Liguori، نويسنده , , Francesca and Cacciarini، نويسنده , , Martina and Goti، نويسنده , , Andrea، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
Practical syntheses of nitrone 8 by two different approaches from sugars are reported. Its use as a versatile intermediate in highly selective 1,3-dipolar cycloaddition reactions constitutes the key step for novel total syntheses of hyacinthacine A2 (3) and 7-deoxycasuarine (20) by simple transformations of a common isoxazolidine adduct.
Keywords :
Nitrones , enantiospecific synthesis , carbohydrates , glycosidases inhibitors , Pyrrolizidine alkaloids
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
