An efficient heterogeneous Heck reaction promoted by a new assembled catalyst of palladium and non-cross-linked amphiphilic polymer

A newly assembled insoluble catalyst 1b composed of palladium and non-cross-linked amphiphilic polymer was developed. It was named PdAS-V: a supramolecular complex of (NH4)2PdCl4 (2) and poly[(N-isopropyla̱crylamide)5̱-co-(4-diphenyls̱tyrylphosphine)] (3b). The use of 8.0×10−7–5.0×10−5 mol equiv. of PdAS-V efficiently catalyzed the Heck reaction of aryl iodides with acrylates and styrenes. The turnover number of PdAS-V reached up to 1,150,000, and the catalyst was recycled five times without any decrease in its activity.