Author/Authors :
Quiroz-Garc??a، نويسنده , , Beatriz and Hern?ndez، نويسنده , , Liliana and Toscano، نويسنده , , Rubén A. and Sterner، نويسنده , , Olov and Delgado، نويسنده , , Guillermo، نويسنده ,
Abstract :
The novel pentacyclic compound cyclotokinolide B was obtained from the natural phthalide tokinolide B under basic conditions, via the chemoselective γ-enol lactone opening followed by a Michael addition of the generated carbanion to the enone and subsequent equilibration. This result confirms that some dimeric phthalides undergo intramolecular cyclizations in basic media.
