Title of article
Base-catalyzed intramolecular condensation of tokinolide B
Author/Authors
Quiroz-Garc??a، نويسنده , , Beatriz and Hern?ndez، نويسنده , , Liliana and Toscano، نويسنده , , Rubén A. and Sterner، نويسنده , , Olov and Delgado، نويسنده , , Guillermo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
2509
To page
2512
Abstract
The novel pentacyclic compound cyclotokinolide B was obtained from the natural phthalide tokinolide B under basic conditions, via the chemoselective γ-enol lactone opening followed by a Michael addition of the generated carbanion to the enone and subsequent equilibration. This result confirms that some dimeric phthalides undergo intramolecular cyclizations in basic media.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1661301
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