Title of article :
A facile synthesis of 4- and 6-chloromethyl-1H-indole-2-carboxylates: replacement of a sulfonic acid functionality by chlorine
Author/Authors :
Pete، نويسنده , , Béla and Parlagh، نويسنده , , Gyula، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
Valuable new synthetic intermediates, 4- or 6-chloromethyl-1H-indole-2-carboxylates, were prepared by the elimination of SO2 from 2-ethoxycarbonyl-1H-indole-4- or 6-methanesulfonic acids, respectively, which are easily accessible by Fischer-type indolization.
Keywords :
Fischer synthesis , 4-(chloromethyl)indoles , 6-(chloromethyl)indoles , Desulfination
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
