Title of article :
The synthesis of β-lactams via a one-pot Reformatsky reaction of imines promoted by Zn/Cp2TiCl2 (cat.)
Author/Authors :
Chen، نويسنده , , Lei and Zhao، نويسنده , , Gang and Ding، نويسنده , , Yu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
In the presence of Zn/Cp2TiCl2 (cat.) α-bromoacetates, γ-bromocrotonates or α-bromomethylacrylates react with imines in one-pot to form β-lactams, 3-vinyl-β-lactams or α-methylene-γ-lactams, respectively, at room temperature without the need for pretreatment of the solvent and Zn.
Keywords :
imines , azetidinones , Reformatsky reaction , biscyclopentadienyltitanium dichloride
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters