Title of article
Mono(6A-N-allylamino-6A-deoxy)perphenylcarbamoylated β-cyclodextrin: synthesis and application as a chiral stationary phase for HPLC
Author/Authors
Lai، نويسنده , , Xianghua and Ng، نويسنده , , Siu-Choon، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
2657
To page
2660
Abstract
A novel cyclodextrin derivative: mono(6A-N-allylamino-6A-deoxy)perphenylcarbamoylated β-cyclodextrin was synthesized. Hydrosilylation with (EtO)3SiH and then reaction of the reactive siloxane with pristine silica gel afforded a facile entry into a durable, structurally well-defined chiral stationary phase capable of enantioseparation of a variety of racemic drugs.
Keywords
cyclodextrin , Hydrosilylation , Enantioseparation , chiral stationary phases
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1661399
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