Author/Authors :
Saitoh، نويسنده , , Toshikazu and Suzuki، نويسنده , , Toshio and Onodera، نويسنده , , Norihiro and Sekiguchi، نويسنده , , Hideya and Hagiwara، نويسنده , , Hisahiro and Hoshi، نويسنده , , Takashi، نويسنده ,
Abstract :
An efficient and versatile method for the stereospecific construction of α,ω-cis- and α,ω-trans-disubstituted eight- and nine-membered cyclic ethers was developed. Cyclization of the hydroxy epoxides promoted by Eu(fod)3 proceeded via an SN2 process and exo mode to provide the corresponding cyclic ethers in excellent yields.
Keywords :
oxocenes , oxonenes , regioselection , hydroxy epoxides , cyclization
