Author/Authors :
Hojo، نويسنده , , Hironobu and Haginoya، نويسنده , , Eiichiro and Matsumoto، نويسنده , , Yoshiyuki and Nakahara، نويسنده , , Yoshiaki and Nabeshima، نويسنده , , Kazuki and Toole، نويسنده , , Bryan P. and Watanabe، نويسنده , , Yasushi، نويسنده ,
Abstract :
Peptide thioester carrying N-linked core pentasaccharide was prepared by the Fmoc solid-phase method with a combination of the benzyl-protection strategy at the carbohydrate portion. The obtained peptide thioester was successfully used for the synthesis of the first Ig domain of emmprin composed of 61 amino acid residues.