• Title of article

    From terminal alkynes directly to branched amines

  • Author/Authors

    Garcia-Castro، نويسنده , , Ivette and Tillack، نويسنده , , Annegret and Hartung، نويسنده , , Christian G and Beller، نويسنده , , Matthias، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    5
  • From page
    3217
  • To page
    3221
  • Abstract
    The one-pot synthesis of several branched secondary aliphatic amines is described. Hydroamination of terminal alkynes with aliphatic primary amines in the presence of Cp2Ti(η2-Me3SiCCSiMe3) gives the corresponding aldimines as intermediates. Reaction of these in situ produced aldimines with organolithium reagents (n-BuLi, PhLi) provides the α-branched amines in an easy way in upto 78% overall yield.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2003
  • Journal title
    Tetrahedron Letters
  • Record number

    1661729

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1661729