• Title of article

    Desilylation versus elimination reactions of β-hydroxysilanes: effect of substituents on silicon

  • Author/Authors

    Hudrlik، نويسنده , , Paul F. and Gebreselassie، نويسنده , , Petros and Tafesse، نويسنده , , Laykea and Hudrlik، نويسنده , , Anne M.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    4
  • From page
    3409
  • To page
    3412
  • Abstract
    β-Hydroxy(trimethyl)silanes undergo stereospecific desilylation reactions to give alcohols using KOt-Bu in DMSO:H2O, but the reactions are very slow. In this work, desilylation reactions are facilitated using β-hydroxysilanes with (i-PrO)Me2Si, HMe2Si, or HOMe2Si groups (e.g. 9→11). The (HO)Me2Si compound (10) (or alkoxide) was shown to be an intermediate, and undergoes β elimination less readily than the Me3Si compound (7).
  • Keywords
    ?-hydroxysilane , Desilylation , elimination
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2003
  • Journal title
    Tetrahedron Letters
  • Record number

    1661834

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1661834