Title of article
LiClO4- or LiOTf-accelerated 1,3-dipolar cycloaddition reactions: a facile synthesis of cis-fused chromano[4,3-c]isoxazoles
Author/Authors
Yadav، نويسنده , , J.S. and Reddy، نويسنده , , B.V.S. and Narsimhaswamy، نويسنده , , D. and Narsimulu، نويسنده , , K. and Kunwar، نويسنده , , A.C.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
3697
To page
3700
Abstract
Acetonitrile solutions of lithium perchlorate or lithium triflate are found to accelerate considerably the intramolecular 1,3-dipolar cycloaddition reactions of nitrones derived in situ from hydroxylamines and the O-prenyl derivatives of salicylaldehydes to afford enhanced rates and improved yields of tetrahydrochromano[4,3-c]isoxazole derivatives with high diastereoselectivity. The stereochemistry of the products has been assigned by using extensive NMR studies.
Keywords
Nitrones , Lithium salts , intramolecular cycloaddition , chromanoisoxazoles
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662006
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