Title of article :
Solvent-free synthesis of 4-aryl substituted 5-alkoxycarbonyl-6-methyl-3,4-dihydropyridones under microwave irradiation
Author/Authors :
Rodr??guez، نويسنده , , Hortensia and Suarez، نويسنده , , Margarita and Pérez، نويسنده , , Rolando and Petit، نويسنده , , Alain and Loupy، نويسنده , , André، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
4-Aryl substituted 5-alkoxycarbonyl-6-methyl-3,4-dihydropyridones have been prepared in one-pot condensation from Meldrumʹs acid, methyl acetoacetate and the appropriate benzaldehyde in the presence of ammonium acetate using microwave irradiation without solvent. This rapid method produced pure products in high yields (81–91%) due essentially to a specific non-thermal microwave effect (17–28%) by conventional heating under the same conditions.
Keywords :
microwave irradiation , dihydropyridones , solvent-free synthesis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters