Author/Authors :
Aragonès، نويسنده , , S??lvia and Bravo، نويسنده , , Fernando Perez-Diaz، نويسنده , , Yolanda and Matheu، نويسنده , , Ma? Isabel and Castill?n، نويسنده , , Sergio، نويسنده ,
Abstract :
l-Isonucleosides 17 and 19 were stereoselectively synthesised from (S)-glycidol by two different procedures. The key step was the synthesis of a chiral dihydrofuran which was carried out by oxidation/elimination of 8 and by ring-closing metathesis of diene 10. The procedure can be applied to the synthesis of both enantiomers.
