Title of article
Synthesis of hexahydrochromeno[4,3-b]azepine derivatives
Author/Authors
Pavé، نويسنده , , Grégoire and Léger، نويسنده , , Jean-Michel and Jarry، نويسنده , , Christian and Viaud-Massuard، نويسنده , , Marie-Claude and Guillaumet، نويسنده , , Gérald، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
4219
To page
4222
Abstract
Synthesis of optically pure (6aR,11aS)-7,8,9,10,11,11a-hexahydro-5-oxa-11-azacyclohepta[a]naphthalen-6a-ylamine from 2-cyano-6-oxazolopiperidine is described via the CN(R,S) strategy. The lithium aluminium hydride involves a one-pot reduction and a ring-enlargement process. Absolute configuration of the tricyclic derivative is unambiguously established by X-ray crystal structure analyses.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662311
Link To Document