Title of article
A mild and efficient synthesis of 4-aryl-quinolin-2(1H)-ones via a tandem amidation/Knoevenagel condensation of 2-amino-benzophenones with esters or lactones
Author/Authors
Wang، نويسنده , , Jianji and Discordia، نويسنده , , Robert P. and Crispino، نويسنده , , Gerard A. and Li، نويسنده , , Jun and Grosso، نويسنده , , John A. and Polniaszek، نويسنده , , Richard and Truc، نويسنده , , Vu C.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
4271
To page
4273
Abstract
Using LiHMDS as the base, a tandem amidation/Knoevenagel condensation of 2-aminobenzophenones with α-methylene esters or lactones gives 4-aryl-quinolin-2(1H)-ones in 65–96% yield. This method is mild, highly efficient, and amenable to scaleup.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662342
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