Title of article
Microwave-assisted multi-component synthesis of fused 3-aminoimidazoles
Author/Authors
Ireland، نويسنده , , Sarah M. and Tye، نويسنده , , Heather and Whittaker، نويسنده , , Mark، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
4369
To page
4371
Abstract
A variety of fused 3-aminoimidazoles have been synthesised by a microwave assisted Ugi three-component coupling (3cc) reaction catalysed by scandium triflate in methanol as solvent. Yields of 33–93% have been achieved after just 10 min of microwave irradiation using a simple one-stage procedure. The methodology described is suitable for the rapid and efficient synthesis of a range of fused heterocycles of pharmacological interest.
Keywords
Multi-component reaction , Scandium triflate , heterocycle , microwave , Imidazole , Ugi
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662403
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