Title of article
A concise synthesis of a new xylyl-biaryl diphosphine ligand for asymmetric hydrogenation of ketones
Author/Authors
Henschke، نويسنده , , Julian P. and Zanotti-Gerosa، نويسنده , , Antonio and Moran، نويسنده , , Paul and Harrison، نويسنده , , Paul E. Mullen، نويسنده , , Brendan and Casy، نويسنده , , Guy and Lennon، نويسنده , , Ian C.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
4379
To page
4383
Abstract
A concise synthesis of a symmetrical biaryl diphosphine ligand bearing 3,5-dimethylphenyl substituents at phosphorus is described. The ruthenium catalysts [diphosphine RuCl2 diamine] containing the new ligand Xyl-TetraPHEMP were found to be as active and as selective as the state-of-the-art catalysts for homogeneous asymmetric ketone hydrogenation.
Keywords
asymmetric hydrogenation , biaryl phosphines , Chiral ligands , ketone hydrogenation
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662409
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