Title of article
A concise synthesis of protected diethyl 1-amino-2-hydroxyalkylphosphonates
Author/Authors
B?a?ewska، نويسنده , , Katarzyna and Sikora، نويسنده , , Dorota and Gajda، نويسنده , , Tadeusz، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
4747
To page
4750
Abstract
An efficient diastereoselective synthesis of 5-substituted (2-thioxo-oxazolidin-4-yl)phosphonic acid diethyl esters from metallated diethyl isothiocyanomethylphosphonate and aldehydes has been developed. The three-step transformation of oxazolidine-2-thione derivatives into N-Boc 1-amino-2-hydroxyalkylphosphonic acid diethyl esters is also described.
Keywords
oxazolidine-2-thiones , oxazolidin-2-one , diethyl 1-amino-2-hydroxyalkylphosphonates
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662629
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