Title of article :
A stereocontrolled total synthesis of methyl (±)-O-methylpodocarpate
Author/Authors :
Roy، نويسنده , , Arnab and Paul، نويسنده , , Tapas and Drew، نويسنده , , Michael G.B. and Mukherjee، نويسنده , , Debabrata، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
A stereocontrolled total synthesis of methyl (±)-O-methyl podocarpate (4) has been successfully accomplished using the trans-fused diester 21 as a key intermediate. Intramolecular Michael reaction of the enone-diester 18 afforded the cis-fused keto-diester 19 in high yield which was stereoselectively converted into 21 via the enone 20.
Keywords :
Terpenes , Esters , conjugate addition , Alkylation , Michael reaction
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
