Title of article
Liquid-phase parallel synthesis of tetrahydro-β-carbolines
Author/Authors
Yeh، نويسنده , , Wen-Ben and Lin، نويسنده , , Mei-Jung and Sun، نويسنده , , Chung-Ming، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
4923
To page
4926
Abstract
Parallel synthesis of β-carbolines on soluble polyethylene glycol (PEG-OH) support is demonstrated. One-pot condensation of polymer-bound tryptophan residues with various aldehydes and ketones has been carried out in the presence of p-TSA as a catalyst to deliver immobilized 1,2,3,4-tetrahydro-β-carbolines. Subsequent disengagement of the appendant from the polymer support afforded the desired products in good yield and acceptable purity.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662730
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