Title of article
Synthesis of α-amino γ-butyrolactone derivatives by aziridination of α-ylidene γ-butyrolactones
Author/Authors
Gasperi، نويسنده , , Tecla and Loreto، نويسنده , , M.Antonietta and Tardella، نويسنده , , Paolo A. and Veri، نويسنده , , Elisabetta، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
4953
To page
4956
Abstract
The reactions of exocyclic α,β-unsaturated γ-lactones with NsONHCO2Et and CaO produce N-(ethoxycarbonyl) spiroaziridino γ-lactones. By reaction with acetic acid these products give ring opening reaction and acetylated N-protected α-amino γ-butyrolactones are obtained. The ring opening reaction is quantitative and highly regioselective.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662740
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