Title of article
Efficient deprotection of N-benzyloxycarbonyl group from amino acids by hydroxyapatite-bound Pd catalyst in the presence of molecular hydrogen
Author/Authors
Murata، نويسنده , , Makoto R. Hara، نويسنده , , Takayoshi and Mori، نويسنده , , Kohsuke and Ooe، نويسنده , , Masahiko and Mizugaki، نويسنده , , Tomoo and Ebitani، نويسنده , , Kohki and Kaneda، نويسنده , , Kiyotomi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
4981
To page
4984
Abstract
Hydroxyapatite-bound Pd catalyst was found to be highly effective for the deprotection of N-benzyloxycarbonyl group from amino acids in the presence of molecular hydrogen. The catalyst was also applicable to the hydrogenolysis of a sterically encumbered core-Z-protected poly(amido amine) dendrimer, affording the dendritic amino compound in 99% yield.
Keywords
Hydrogenolysis , benzyloxycarbonyl , dendrimer , Hydroxyapatite , heterogeneous palladium catalyst
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1662760
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