Author/Authors :
Portlock، نويسنده , , David E. and Naskar، نويسنده , , Dinabandhu and West، نويسنده , , Laura and Ostaszewski، نويسنده , , Ryszard and Chen، نويسنده , , Jack J.، نويسنده ,
Abstract :
Five-dimensional libraries of dipeptide amides are readily prepared using a solid-phase tandem Petasis–Ugi multi-component condensation protocol on either a RINK amine or Universal RINK isonitrile resin. The method is practical and can be automated to prepare a large number of compounds useful for high throughput biological screening.
