Title of article :
Solid-phase synthesis: a linker for side-chain anchoring of arginine
Author/Authors :
Garc?́a، نويسنده , , Oscar and Nicol?s، نويسنده , , Ernesto and Albericio، نويسنده , , Fernando، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
A new linker based on a chroman system is described for the side-chain anchoring of Arg and other guanidine-containing molecules. The system is compatible with the Fmoc/tBu solid-phase strategy, because the release of the final product is achieved by treatment with TFA in the presence of scavengers.
Keywords :
benzofuran , Benzopyran , Handle , Linker , Protecting group , Combinatorial chemistry , solid phase
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters