Author/Authors :
Marcos ، نويسنده , , I.S and Laderas، نويسنده , , M and D??ez، نويسنده , , D and Basabe، نويسنده , , P and Moro، نويسنده , , R.F and Garrido، نويسنده , , N.M and Urones، نويسنده , , J.G، نويسنده ,
Abstract :
An efficient synthesis of (−)-chrysolic acid and (+)-isofregenedol has been achieved from zamoranic acid and sclareol. The characteristic tetrahydronaphtalenic system was obtained by use of a cationic rearrangement of bicyclic systems adequately functionalized. The absolute configuration of the natural products was established using Sharpless asymmetric epoxidation.
