Author/Authors :
Liu، نويسنده , , Shuhua and Zhang، نويسنده , , Zhihua and Wang، نويسنده , , Yubo and Wang، نويسنده , , Fuke and Han، نويسنده , , Ming-Yong، نويسنده ,
Abstract :
Monodisperse Au at SiO2 nanoparticles has been functionalized with carboxylic groups for further bioconjugation with amino-terminated oligonucleotides. The oligonucleotide-modified Au at SiO2 nanoprobes have been applied in the fast colorimetric DNA based on the sequence-specific hybridization properties of DNA. Self-assembling behavior of Au at SiO2 nanoparticles was also investigated.
Keywords :
Surface functionalization , Bioconjugation , Gold nanoparticles , Silica coating
