Title of article
Lipase-catalyzed remote kinetic resolution of arylic nitriles with adjacent quaternary chiral center and the determination of their absolute configuration
Author/Authors
Im، نويسنده , , Dai Sig and Cheong، نويسنده , , Chan Seong and Lee، نويسنده , , So Ha، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
13
From page
131
To page
143
Abstract
Enzymatic resolution of tertiary arylic nitrile alcohols (1–8) by lipases from Pseudomonas cepacia (PCL), Pseudomonas flurescens (LAK, made by Amano Enzyme Co. Ltd.), Pseudomonas fluorescens (PFL) and Candida rugosa (CRL) were described, and the absolute configuration of the resolved chiral alcohols (1–8) were determined by chemical transformations to the compounds with known configuration.
Keywords
Lipase , Arylic nitrile , RESOLUTION , biocatalyst
Journal title
Journal of Molecular Catalysis B Enzymatic
Serial Year
2003
Journal title
Journal of Molecular Catalysis B Enzymatic
Record number
1709896
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