The biocatalytic oxidation of thujopsene by plant cultured-cells

The biotransformation of thujopsene (1) using plant suspension cultured-cells was investigated. It was found that the cultured-cells oxidate thujopsene to 3β-hydroxy-4-thujopsene (2), mayurone (3), and 3β-epoxythujopsan-5β-ol (4). And, it was shown that the biotransformation activity of cultured-cells of Hibiscus cannabinus is significantly higher than that of cultured-cells of Nicotiana tabacum and Catharanthus roseus.