Title of article
Ionic liquids: efficient additives for Candida rugosa lipase-catalysed enantioselective hydrolysis of butyl 2-(4-chlorophenoxy)propionate
Author/Authors
Mahesh K and Mohile، نويسنده , , Swapnil S. and Potdar، نويسنده , , Mahesh K and Harjani، نويسنده , , Jitendra R and Nara، نويسنده , , Susheel J and Salunkhe، نويسنده , , Manikrao M، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
185
To page
188
Abstract
The Candida rugosa lipase-catalysed enantioselective hydrolysis of butyl 2-(4-chlorophenoxy)propionate 1 has been carried out in aqueous buffer with ionic liquid as co-solvent. The influence of ionic liquid on the catalytic efficiency and selectivity has been studied, using both hydrophobic and hydrophilic ionic liquids. The markedly enhanced enantioselectivity towards the R enantiomer of substrate 1 is observed under optimum additive conditions (1:1 composition of ionic liquid and buffer). Hydrophobic ionic liquids offered almost quantitative conversions with ee ≥ 99%.
Keywords
Ionic liquid , Enantioselective hydrolysis , Candida rugosa lipase , Butyl 2-(4-chlorophenoxy)propionate , Co-solvent
Journal title
Journal of Molecular Catalysis B Enzymatic
Serial Year
2004
Journal title
Journal of Molecular Catalysis B Enzymatic
Record number
1710321
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