Title of article
Chemoenzymatic preparative separation of silybins A and B
Author/Authors
K?en، نويسنده , , Vladim?r and Ga??k، نويسنده , , Radek and Purchartov?، نويسنده , , Kate?ina and Marhol، نويسنده , , Petr and Biedermann، نويسنده , , David and Sedmera، نويسنده , , Petr، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
5
From page
247
To page
251
Abstract
Robust and scalable chemoenzymatic procedure for obtaining gram amounts of pure silybin A and B within one week is described. It consists of the preparation of 23-O-β-pentaacetyl-galactopyranosides of silybin, their separation by silica gel chromatography, deprotection, and enzymatic sugar removal with β-galactosidase.
Keywords
?-Galactosidase , Silibinin , Silybin A , Diastereomer separation , glycosylation , Silymarin
Journal title
Journal of Molecular Catalysis B Enzymatic
Serial Year
2009
Journal title
Journal of Molecular Catalysis B Enzymatic
Record number
1714266
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