Title of article :
Chemoenzymatic preparative separation of silybins A and B
Author/Authors :
K?en، نويسنده , , Vladim?r and Ga??k، نويسنده , , Radek and Purchartov?، نويسنده , , Kate?ina and Marhol، نويسنده , , Petr and Biedermann، نويسنده , , David and Sedmera، نويسنده , , Petr، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2009
Abstract :
Robust and scalable chemoenzymatic procedure for obtaining gram amounts of pure silybin A and B within one week is described. It consists of the preparation of 23-O-β-pentaacetyl-galactopyranosides of silybin, their separation by silica gel chromatography, deprotection, and enzymatic sugar removal with β-galactosidase.
Keywords :
?-Galactosidase , Silibinin , Silybin A , Diastereomer separation , glycosylation , Silymarin
Journal title :
Journal of Molecular Catalysis B Enzymatic
Journal title :
Journal of Molecular Catalysis B Enzymatic
