Title of article
Ionic liquid co-lyophilized enzyme for biocatalysis in organic solvent: Remarkably enhanced activity and enantioselectivity
Author/Authors
Lee، نويسنده , , Jae Kwan and Kim، نويسنده , , Mahn-Joo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2011
Pages
4
From page
275
To page
278
Abstract
The room temperature solid-phase ionic liquid (RTSPIL) co-lyophilized enzyme exhibited markedly enhanced activity in organic solvent. The enzyme co-lyophilized with a dodecyl-imidazolium salt was 660-fold more active compared to its RTSPIL-free counterpart. The activity enhancement by RTSPILs was mainly attributable to the reduced particle sizes and improved dispersion of enzymes suspended in organic solvent. Also, the RTSPIL co-lyophilized enzyme displayed significantly enhanced enantioselectivity. Its enantioselectivity was 2.5-fold higher than that of its RTSPIL-free counterpart.
Keywords
Ionic liquid , Biocatalysis , Trasesterification , Lyophilization , Room temperature solid-phase
Journal title
Journal of Molecular Catalysis B Enzymatic
Serial Year
2011
Journal title
Journal of Molecular Catalysis B Enzymatic
Record number
1714997
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