Title of article :
Kinetic resolution of 5H-pyrrolo[1,2-a]imidazol-7-ol, 6,7-dihydro under continuous flow conditions: An intermediate for chiral ionic liquids synthesis
Author/Authors :
De Miranda، نويسنده , , Amanda S. and Gomes، نويسنده , , Juliana C. and Rodrigues Jr.، نويسنده , , Manoel T. and Costa، نويسنده , , Ingrid C.R. and Almeida، نويسنده , , Wanda P. and Lopes، نويسنده , , Raquel de O. and Miranda، نويسنده , , Leandro S.M. and Coelho، نويسنده , , Fernando and de Souza، نويسنده , , Rodrigo O.M.A.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2013
Abstract :
In this letter we disclosed an efficient method for the kinetic resolution of an imidazole derivate both in batch and continuous flow conditions. This imidazole derivative has been described to have important applications in different fields and it was obtained, in its enantiomerically pure form, with excellent enantiomeric excess, good yields and short time using continuous flow conditions.
Keywords :
Flow chemistry , Lipases , kinetic resolution , Ionic liquids
Journal title :
Journal of Molecular Catalysis B Enzymatic
Journal title :
Journal of Molecular Catalysis B Enzymatic
