Title of article
Arthrobacter sp. lipase catalyzed kinetic resolution of BINOL: The effect of substrate immobilization
Author/Authors
Gupta، نويسنده , , Pankaj and Rouf، نويسنده , , Abdul and Shah، نويسنده , , Bhahwal Ali and Mahajan، نويسنده , , Neha and Chaubey، نويسنده , , Asha and Taneja، نويسنده , , Subhash Chandra، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2014
Pages
5
From page
35
To page
39
Abstract
(S)-1,1′-Binaphthyl-2,2′-diol was prepared in high optical purity (∼98%) via Arthrobacter sp. lipase (MTCC No. 5125) catalyzed kinetic resolution. The immobilization of the substrate on a solid inert support significantly improved the enantioselectivity factor (E) by almost sixfolds, i.e. from ∼27 to >180. The effect of acyl substituents and co-solvents were also studied.
Keywords
(S)-1 , 1?-Binaphthyl-2 , 2?-diol , kinetic resolution , Arthrobacter sp. lipase , solid support , Co-solvent
Journal title
Journal of Molecular Catalysis B Enzymatic
Serial Year
2014
Journal title
Journal of Molecular Catalysis B Enzymatic
Record number
1718505
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