Fabrication of a highly sensitive sensor electrode using a nano-gapped gold particle film

Controlling a gap between electrodes arranged in nanometer size has a great potential for a highly sensitive detection. We have successfully fabricated a sensor based on a nano-gapped gold particle film consisting of gold nanoparticle–alkylchain–gold nanoparticle repeated sequences in a straightforward manner. Here we report on its application to direct DNA analysis, enabling us to read out a specific complementary DNA through electronic protocols.