Effects of colored noise and noise delay on a calcium oscillation system

As a calcium oscillations system is in steady state, the effects of colored noise and noise delay on the system is investigated using stochastic simulation methods. The results indicate that: (1) the colored noise can induce coherence bi-resonance phenomenon. (2) there exist three peaks in the R – τ 0 ( R is the reciprocal coefficient of variance, and τ 0 is the self-correlation time of the colored noise) curves. For the same noise intensity Q = 1 , the Gaussian colored noise can induce calcium spikes but the white noise cannot do this. (3) the delay time can improve noise induced spikes regularity as τ 0 is small, and R has a significant minimum with increasing τ as τ 0 is large. (4) large values of ζ reduce noise induced spikes regularity.