Title of article :
Percutaneous Coronary Interventions in Facilities Without Cardiac Surgery On Site: A Report From the National Cardiovascular Data Registry (NCDR)
Author/Authors :
Kutcher، نويسنده , , Michael A. and Klein، نويسنده , , Lloyd W. and Ou، نويسنده , , Fang-Shu and Wharton Jr، نويسنده , , Thomas P. and Dehmer، نويسنده , , Gregory J. and Singh، نويسنده , , Mandeep and Anderson، نويسنده , , H. Vernon and Rumsfeld، نويسنده , , John S. and Weintraub، نويسنده , , William S. and Shaw، نويسنده , , Richard E. and Sacrinty، نويسنده , , Matthew T. and Woodward، نويسنده , , Albert and Peterson، نويسنده , , Eric D. and Brindis، نويسنده , , Ralph G.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2009
Pages :
9
From page :
16
To page :
24
Abstract :
New and emerging therapies might provide benefit in patients with pulmonary arterial hypertension. Their efficacy and safety will be compared with existing combination therapies in randomized clinical trials. Appropriate end points for these trials need to be identified: these will include exercise testing, the composite end point of time to clinical worsening, and hemodynamic markers, including advanced imaging modalities and biomarkers. Quality-of-life questionnaires are useful and important secondary end points; pulmonary arterial hypertension-specific questionnaires are currently being developed. Advantages and disadvantages of various trial designs, including placebo-controlled monotherapy or add-on trials, noninferiority studies, and withdrawal trials are also discussed.
Keywords :
percutaneous coronary intervention , Cardiac surgery , outcomes analysis
Journal title :
JACC (Journal of the American College of Cardiology)
Serial Year :
2009
Journal title :
JACC (Journal of the American College of Cardiology)
Record number :
1744785
Link To Document :
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