Author/Authors :
Zardi، نويسنده , , Enrico M. and Abbate، نويسنده , , Antonio and Zardi، نويسنده , , Domenico Maria and Dobrina، نويسنده , , Aldo and Margiotta، نويسنده , , Domenico and Van Tassel، نويسنده , , Benjamin W. and Afeltra، نويسنده , , Antonella and Sanyal، نويسنده , , Arun J.، نويسنده ,
Abstract :
Cirrhotic cardiomyopathy is a clinical syndrome in patients with liver cirrhosis characterized by an abnormal and blunted response to physiologic, pathologic, or pharmacologic stress but normal to increased cardiac output and contractility at rest. As many as 50% of cirrhotic patients undergoing liver transplantation show signs of cardiac dysfunction, and 7% to 21% of deaths after orthotopic liver transplantation result from overt heart failure. In this review, we critically evaluate the existing literature on the pathophysiology and clinical implications of cirrhotic cardiomyopathy.
Keywords :
Cardiomyocyte , Vascular Dysfunction , Cirrhosis , Portal Hypertension
