Title of article
The role of surface wettability and surface charge of electrosprayed nanoapatites on the behaviour of osteoblasts
Author/Authors
Thian، نويسنده , , E.S. and Ahmad، نويسنده , , Z. and Huang، نويسنده , , J. and Edirisinghe، نويسنده , , M.J. and Jayasinghe، نويسنده , , S.N. and Ireland، نويسنده , , D.C. and Brooks، نويسنده , , R.A. and Rushton، نويسنده , , N. and Bonfield، نويسنده , , W. M. Best، نويسنده , , S.M.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
6
From page
750
To page
755
Abstract
A new deposition method is presented, based on electrospraying, that can build bioceramic structures with desirable surface properties. This technology allows nanoapatite crystals, including hydroxyapatite (nHA), carbonate-substituted HA (nCHA) and silicon-substituted HA (nSiHA), to be electrosprayed on glass substrates. Human osteoblast cells cultured on nSiHA showed enhanced cell attachment, proliferation and protein expression, namely alkaline phosphatase, type 1 collagen and osteocalcin, as compared to nHA and nCHA. The modification of nanoapatite by the addition of silicon into the HA lattice structure renders the electrosprayed surface more hydrophilic and electronegatively charged.
Keywords
Osteoblasts , Silicon , CARBONATE , Nanoapatites , Electrospraying
Journal title
Acta Biomaterialia
Serial Year
2010
Journal title
Acta Biomaterialia
Record number
1753591
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