Author/Authors :
Raj Kumar، Vaya نويسنده Department of Pharmacology, Pacific college of Pharmacy, Pacific University, Udaipur (Rajasthan) , , I، Singhvi نويسنده Department of Pharmacology, Pacific college of Pharmacy, Pacific University, Udaipur (Rajasthan) , , Rajesh، Vaya نويسنده Department of Pharmacology, Pacific college of Pharmacy, Pacific University, Udaipur (Rajasthan) , , J، Dwivedi نويسنده Department of Pharmacology, Pacific college of Pharmacy, Pacific University, Udaipur (Rajasthan) , , Dipesh، Jain نويسنده Department of Pharmacology, Pacific college of Pharmacy, Pacific University, Udaipur (Rajasthan) ,
Abstract :
The epilepsies are common and frequently devastating disorders, affecting approximately 2.5 million people in the United States alone. More than 40 distinct forms of epilepsy have been identified. Epileptic seizures often cause transient impairment of consciousness, leaving the individual at risk of bodily harm and often interfering with education and employment. Therapy is symptomatic in that available drugs do not inhibit seizures, but neither effective prophylaxis nor cure is available. Compliance with medication is a major problem because of the need for long-term therapy together with unwanted effects of many drugs. Although many treatments are available, much effort is being devoted to novel approaches. Many of these approaches centre on elucidating the genetic causes and the cellular and molecular mechanisms by which a normal brain becomes epileptic, insights that promise to provide molecular targets for both symptomatic and preventive therapies.
