Title of article :
Risk factors for multiple myeloma: A hospital-based case–control study in Northwest China
Author/Authors :
Wang، نويسنده , , Qixia and Wang، نويسنده , , Yiwei and Ji، نويسنده , , Zhaohua and Chen، نويسنده , , Xiequn and Pan، نويسنده , , Yaozhu and Gao، نويسنده , , Guangxun and Gu، نويسنده , , Hongtao and Yang، نويسنده , , Yang and Choi، نويسنده , , Bernard C.K. and Yan، نويسنده , , Yongping، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2012
Pages :
6
From page :
439
To page :
444
Abstract :
Background stinctive racial/ethnic and geographic distribution of multiple myeloma (MM) suggests that both family history and environmental factors may contribute to its development. s ital-based case–control study consisting of 220 confirmed MM cases and 220 individually matched patient controls, by sex, age and hospital was carried out at 5 major hospitals in Northwest China. A questionnaire was used to obtain information on demographics, family history, and the frequency of food items consumed. s on multivariate analysis, a significant association between the risk of MM and family history of cancers in first degree relatives was observed (OR = 4.03, 95% CI: 2.50–6.52). Fried food, cured/smoked food, black tea, and fish were not significantly associated with the risk of MM. Intake of shallot and garlic (OR = 0.60, 95% CI: 0.43–0.85), soy food (OR = 0.52, 95% CI: 0.36–0.75) and green tea (OR = 0.38, 95% CI: 0.27–0.53) was significantly associated with a reduced risk of MM. In contrast, intake of brined vegetables and pickle was significantly associated with an increased risk (OR = 2.03, 95% CI: 1.41–2.93). A more than multiplicative interaction on the decreased risk of MM was found between shallot/garlic and soy food. sion udy in Northwest China found an increased risk of MM with a family history of cancer, a diet characterized by low consumption of garlic, green tea and soy foods, and high consumption of pickled vegetables. The effect of green tea in reducing the risk of MM is an interesting new finding which should be further confirmed.
Keywords :
Multiple myeloma , Risk Factor , Case–control study , Northwest China
Journal title :
Cancer Epidemiology
Serial Year :
2012
Journal title :
Cancer Epidemiology
Record number :
1765856
Link To Document :
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