Title of article
Structural changes of lipoprotein lipids by 1H NMR
Author/Authors
Ala-Korpela، نويسنده , , M. and Oja، نويسنده , , J. and Lounila، نويسنده , , J. and Jokisaari، نويسنده , , J. and Savolainen، نويسنده , , M.J. and Kesنniemi، نويسنده , , Y.A.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
95
To page
100
Abstract
A new procedure for detecting structural changes of lipoprotein lipids is introduced and applied to study native low (LDL) and high density lipoprotein (HDL) particles. The method involves lineshape fitting analyses of specific resonances in proton nuclear magnetic resonance spectra together with numerical derivation of the obtained intensity curves with respect to temperature. In addition to the well-known phase transition of the LDL core cholesterol esters, a novel structural change was revealed in the phospholipid monolayer of both native LDL and HDL particles. The attributes of this phenomenon are discussed.
Journal title
Chemical Physics Letters
Serial Year
1995
Journal title
Chemical Physics Letters
Record number
1774472
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