Author/Authors :
Tresadern، نويسنده , , Gary and McNamara، نويسنده , , Jonathan P and Mohr، نويسنده , , Matthias and Wang، نويسنده , , Hong and Burton، نويسنده , , Neil A and Hillier، نويسنده , , Ian H، نويسنده ,
Abstract :
Although the potential energy barrier for hydrogen transfer is similar for the enzymes liver alcohol dehydrogenase, methylamine dehydrogenase and soybean lipoxygenase, the degree of tunnelling is predicted to differ greatly, and is reflected by their primary kinetic isotope effects.