Author/Authors :
Zhao، نويسنده , , P.D. and Chen، نويسنده , , P. and Tang، نويسنده , , G.Q. and Zhang، نويسنده , , G.L. and Chen، نويسنده , , W.J.، نويسنده ,
Abstract :
We report on the two-photon-excited (TPE) fluorescence spectrum and lifetime of a new chlorin derivative photosensitizer (CDP) in 0.9% NaCl solution with femtosecond laser pulses at 800 nm. The TPE fluorescence spectrum is similar to that obtained by one-photon excitation (OPE). The lifetimes of TPE and OPE fluorescence of CDP are of the order of 4.7 and 5.0 ns, respectively. The two-photon absorption (TPA) cross-section is σ2′≈33.6×10−50 cm4 s photon−1 at 800 nm. Our results indicate that the TPE and OPE photodynamic processes of CDP are basically similar. The lifetime and TPA cross-section suggest CDP may be a potential agent for two photon fluorescent microscopy and imaging as well as a photosensitizer in photodynamic therapy.
