ISOLATION AND ANTIBIOGRAM PATTERN OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS CAUSING WOUND INFECTION

Nosocomial infection is a major problem in the world today. Methicillin- resistant Staphylococcus aureus (MRSA) strains, usually resistant to several antibiotics and also intrinsic resistance to B- lactam antibiotics, shows a particular ability to spread in hospitals and now present in most of the countries. The present study was carried out to investigate the prevalence of MRSA and their rate of resistance to different anti staphylococcal antibiotics. A total of 100 wound samples were screened for MRSA and their antibiotic resistance pattern was performed. Out of 62 isolated strain of S.aureus 28 (45%) were found to be methicillin resistant. Almost all MRSA strains were resistant to penicillin followed by cloxacillin and cephalexin, co-trimoxazole. About 60-70% MRSA strains were resistant to erythromycin, ceftazidime, lincomycin, cephalexin, erythromycin and tetracycline. The determination of prevalence and antibiotic sensitivity pattern of MRSA will help the treating clinicians for first line treatment in referral hospitals.