Title of article
Expression of CDllc in Blood Monocytes as Biomarker for Favorable Response to Antituberculosis Treatment
Author/Authors
Mario C. and Rosas-Taraco، نويسنده , , Adrian G. and Salinas-Carmona، نويسنده , , Mario C. and Revol، نويسنده , , Agnès and Rendon، نويسنده , , Adrian and Caballero-Olin، نويسنده , , Guillermo and Arce-Mendoza، نويسنده , , Alma Y. and Sanchez، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
4
From page
128
To page
131
Abstract
CD11c is involved in Mycobacterium tuberculosis phagocytosis by human macrophages. CD11c has not been evaluated during antituberculosis (anti-TB) treatment. CD11c expression was evaluated on monocytes from peripheral blood leukocytes of pulmonary TB (PTB) patients and healthy controls by flow cytometry, whereas CD11c/Arg47Trp polymorphism was analyzed using polymerase chain reaction-restriction fragment length polymorphism. PTB patients had increased levels of CD11c on blood monocytes as compared to healthy controls. CD11c levels decreased in response to anti-TB treatment. CD11c/Arg47Trp polymorphism is not associated with PTB.
Keywords
Polymorphism , biomarkers , Tuberculosis , CD11c , Antituberculosis treatment
Journal title
Archives of Medical Research
Serial Year
2009
Journal title
Archives of Medical Research
Record number
1796987
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